Probiotics Side Effects Explained

Interestingly, probiotics side effects mean that the good bacteria are working! Here are the most common side effects:

  • diarrhea
  • gas
  • bloating
  • cramps
  • rashes
  • acne

Assuming the adverse effect is relatively minor and does not persist for more than 14 days, then we should be celebrating these side effects! As stated on the box of Dr. Ohhira’s Probiotics.

Temporary reactions such as minor bloating or a mild laxative or constipating effect are signs that the beneficial bacteria are remodeling, detoxifying and improving the gut environment.

Also we should remember, that while these side effects are unpleasant, they are mild compared to those of many pharmaceutical drugs.

3 Ways To Reduce The Side Effects Of Probiotics

1. decrease the dosage

One possible way to reduce the side effects is to reduce the dosage. If you were taking two probiotic pills daily, try taking only one probiotic pill per day. As your body becomes accustomed to the lower dosage, then you can increase the dosage to higher levels. But taking too many probiotic CFUs too quickly may result in probiotic overdose.

2. stay hydrated

Water should help with all the side effects. This is because if you examine the list of side effects:

  • diarrhea
  • gas
  • bloating
  • cramps
  • rashes
  • acne

All of these side effects are ways your body detoxifies, or are signs that your body is having trouble detoxifying. And water is the ultimate detoxification agent. So to help you body detox, stay hydrated!

3. give your body time to adjust

Taking probiotics can kill tons of bad bacterium, replacing them with the good. This can be quite a shock to our body! So give it at least two weeks of feeling the side effects. At that point it makes sense to seek medical attention.

285 comments on “Probiotic Side Effects Come From Cleansing” - Click here to write your comment

  1. nasrin badranloei says:

    your information was very helpful .thank you

  2. Veg mother says:

    Yes, I nothing iced that it is helping my son with his nasal drip immediately the nest morning, bit a back rash occurred causing him to itch, but I figure it was detoxification since he isn’t allergic to any of the raw vegetarian ingredients. Thank you. All other websites say to stop if rash occurs, whereas naturalist say not to…but I like the decrease amount and lots of liquid.

  3. Ashish Mishra says:

    May God Bless you, Whoever you are. You made my day! I was worrying that I could be dealing with something serious here but they’re all the sideeffects of probiotic medicines that I was prescribed.

  4. Connie Dachtler says:

    Thanks for that info, I have really bad IBS and was wondering if the pills were causing it to get worse until I read this. Thanks sooo much for putting tis info out there. It has helped me to better understand the probiotics. :)

  5. Tara says:

    After being on a round of antibiotics, I began giving my (2 yr old) daughter some probiotics – (via a mult-vitamin which includes it & a raw, organic yogurt). After a couple of days, she is experiencing a rash on the back of her neck…. I think I will scale back on her dose. I’ll also monitor the rash & hope it doesn’t get worse!
    Thank you

  6. jess says:

    Thanks so much I have been experiencing all the above.
    Have also had a really gurgly stomach and feeling quite nauseated is this normal?
    Glad I am not alone

  7. Kimberly says:

    This is comforting to know as I have just started taking Restora, which is prescription strength and have had some itching and a couple of bumps or rashes appear. very mild though. I have been diagnosed with a parasite and I am taking 3 rounds of biltricide split apart 3 weeks each round. I am also taking adrenplus, b complex, vitamin D, magnesium, and armour thyroid after testing at alternative dr.
    Thanks and a reply would be greatly appreciated.

  8. SILVANA says:

    how long does it take for the body to adjust & get over the bloating?

  9. Susie says:

    Ive been itching like crazy I thought a bunch of bugs were biting me… I hope this goes away because my stomach feels better, in finally going to the bathroom normally, so I don’t want to discontinue…

    • evan says:

      That’s great you’re tummy is better and you’re more consistent in the bathroom. WOW!

      Sorry about those side effects! If they’re too intense consider decrease the dosage :)

  10. sheri denato says:

    I have not been able to eat fruit for years, without getting uti. I also have been suffering from kidney problems, severe infections and stones. Have been on antibiotics for sinus infections and cipro for all the kidney infections, for so many years, I feel there is no hope.

    • evan says:

      Hi Sheri,

      Your body is engineered to feel right very well to pretty well for most of your life. In most cases people can have a good quality of life or even feel 15 years younger once they get their nutrition, exercise and lifestyle in order.

      I’d recommend trying something new. How To Eat, Move & Be Healthy by Paul Chek is a GREAT book that has a customizable program that will give YOU what YOU need.

      Get your rest (asleep by 10pm!!), go move around (go for a walk & do calisthenics), and try finding food that works better for your body. If I had your type of symptoms, I would consider adding more fat (coconut oil) into my diet and see if it would make me feel better.

      Best of luck – you can do it…I’ve lost over 22 pounds over 8 months and went from feeling down and out to feeling pretty darn good.

      If I can do it, you can too.
      Best of luck!!

  11. Rob says:

    I started to take some of the Dr. Wolz probiotics, one with each meal. I got congested ears and a really sore throat. I also got very tired early in the evening and I got quite achey. Is this sort of thing normal? I am drinking a lot of water. I only took one today and none of the symptoms returned as bad as they were but they are still here.

    • evan says:

      I’m glad the side effects decreased when you reduced the dosage.

      It may be worth just taking the probiotic every other day…I would keep up the water intake and get plenty of rest.

      take care,
      Evan Jerkunica

  12. Viviana Boyer says:

    I was giving my 15 month old 1tsp bio k probiotics. The full serving is 50 billion (yogurt form) my husband accidentally gave him the whole thing while I was out. I’m worried because its definitely too much for a toddler. Should I be alarmed. What should I do??

  13. Annie says:

    I’ve been taking probiotics and a digestive enzyme for a week and just developed a rash on my neck and my stomach seems bloated. Thanks for the advice, I’m glad to hear that’s a sign that it’s working. I’ll drink lots more fluids!

  14. JANELLE SOWELL says:

    Your remarks have really helped. I’m going into the 2nd
    week of two pills a day. I have been suffering with my back
    now and taking this I see a lot of side effects are from starting off with two probiotics. I’m having a lot of trouble
    sleeping, gas bloated stomach hurting. I assume these
    pills are making me hyper therefore I can’t sleep.
    Shall I cut down to one a day for a month? I’m also taking
    Tamoxien (cancer drug and heart) Several friend highly
    recommend these pills. I drink alot of fluid. How long will
    the bloating last? Gas?

    • evan says:

      It really depends on the person how long it will last.

      But as I mentioned above I’d consider reducing the dosage if the side effects are too intense.

  15. Peter says:

    How long do you normal experience these side effects?

    • evan says:

      It depends on the person! Could be a few days, could be whenever you take the probiotic.

      If you keep getting side effects I’d try a lower dose or different probiotic.

      Good luck!

  16. Bridgett says:

    What if I have only taken one (Garden of Life Raw Probiotics, 85 billion cultures, we were instructed to take 3 a day) & it is already causing diarrhea?

    • evan says:

      I’d consider reducing the dosage or reduce it to every other day. 85 Billion is a large dosage and your body may need some time to adjust.

      Good luck!

  17. Nk says:

    After taking probiatic I am going through very bad time. 3 times in emergency. Went through so many tests. Dr. Couldn’t find anything. Gurgling , burping stomach,constipation, lost appetite, lost weight. What’s going on with me . Is this die off

    • evan says:

      That is extremely severe. I doubt it’s only the probiotics, but if they are making things worse then stop taking them.

      Anyway, I’m not a doctor so I can’t say for sure. But listen to your doctors!

  18. Bridget says:

    I took 1 Synthol by Andrew …. I got very sick with all the side effects you mentioned above. I couldn’t get out of the bed or go to work. Extreme stomach cramps. It was severe. I took only one capsule. I had a live blood analysis and this person said I have a very acidic body that means candida was taking over my body. I alkalizer my body and I got better but now I’m craving for sugar again.
    Not sure which probiotic brand shall I take. I’m afraid to go through that pain again. I’m taking Dr Mercola’s probiotic but I don’t think it helps because I got a common women’s problem I got antibiotic for.

    Can you recommend me one please? I appreciate it. Thank you, Bridget.

    • evan says:

      Hey Bridget,

      I’m not sure about how acidic your body is or if you have candida but here’s what I’d do in your situation – and this is a long term way to go…but it will work.

      1) Make sure you’re getting in bed by 10pm each night, and sleep at least 8 hours.
      2) Drink plenty of high quality water
      3) Remove processed foods
      4) Eat non-sugary foods that make you feel good…you really have to pay attention to how each meal makes you feel. This may call for a high fat, high meat diet, or a low fat low meat diet high carb…it depends, there’s no “one size fits all, right for everyone diet”. Consider going on a rotation diet as well.

      If you’re fairly certain you have candida, then I’d read this article on candida.

  19. vicky says:

    Hi,my boy is currently 7months 3 weeks. He has recently lost his appetite in milk intake. Can he consume probiotic? Will it helps to gain weight? He has constipation problem since I introduced solid food during his 6 months old. Will this situation be worse if I would like to let him to consume Probiotic?

    Thank You!

    • evan says:

      Hi Vicky,

      I would consult with your doctor and see what she/he has to say.

      If you can get him back on breast milk that would probably be best. Barring that I’d consider trying Bio Gaia. I’ve heard moms having some success with them.

      Good luck!

  20. sedom says:

    ppl with compromised immuno systems and leaky guts synd. should be not be using ANY probiotics in the beginning of their treatments.

    • evan says:

      Hey Sedom,

      I think it depends. In my case probiotics worked fine for me. That being said, taking probiotics early in a leaky gut situation may not be right for all people. Slow and stead as she goes~!

  21. Peter says:

    I have an Hiatus Hernia which is causing many problems(uncontrolled gasses, burps and farts from top and bottom)I went to see Doctor who prescribed TuZen Probiotics, the pharmacy didn’t have the medicine but they had something else from Life called probiotic Acidophilus, I started taking them 4 days ago and seems that the problem is resolved already, I am tempted to stop the treatment because it has a very bad side effect, which nobody mentions it except one website of many. As soon as i take the medicine a few minutes after I get very bad shakes, I am freezing and I am out for a good ten hours, it is called flu like symptoms. Thought you should know and maybe add it so people can know what to expect.

  22. kim says:

    My 3 yr old is having issues he takes culturelle everyday and Drinks a yogurt drink. He had been sick most of the month with a cold flu whatever. He was co stipated so I have him prune juice anda small dose of miralax and had not stopped pooping he has drank some Gatorade for the electrolites but not a lot of water. Does this sound like he needs to cut back on the yogurt kefir?

  23. gurind says:

    I started taking probiotic and 3 days later I found I m feeling extra pressure for urinate evan I m a dialysis patient

  24. Ana says:

    I too have a hiatal hernia & have been really sick with shakes & then get really really sleepy. My stomach is awful too. i normally would be bloated by mid morning – didn’t matter what I ate & now its not bloated just highly irritated, me too for that matter. I have been on Floragen3 for 3 days & usually by night I feel better but I am producing a lot of gas after dinner. Cant break the capsules so I can only try every other day in hopes of this getting better as I do want this to work. Thank you for the info.

  25. teo says:

    i m using about 4 days probiotics and candida diet,but i have teribble pijn with left side of mijn rib and backache also my immune system is down,is it normal??

    • evan says:

      I’m not a doctor, but based on what happens to my friends/family, that sort of reaction is not uncommon.

      If the detox symptoms are too extreme, I would just ease up on the diet. Maybe do parts of it until your body is ready for it.

      I’ve also found that I detox better when I am:
      a) doing consistent exercise
      b) drinking plenty of water
      c) getting 8+ hours of sleep

      I’ve been there buddy, so hand in there!!

  26. Katie says:

    I started taking probiotics three days ago and the only ‘cleansing’ effect I’ve noticed is that I have to pee like a thousand times a day. Haha. An exaggeration, but noticeably more often anyway.

  27. Rita Bowman says:

    I’m in day four of taking keybiotics by Whole Body Research. I was feeling ok until today when I began feeling nausea, bloating, and a lot of grumbling sounds from my belly. On two occasions I went to the bathroom to throw up but the only thing that came out was a heavy secretion of saliva. I took two tablespoons of Pep-to Bismal and received minor release. I’m thinking tomorrow I will skip a day to see if I feel better and if so I will try an every other day regime. I was not expecting any side effects but this has been the only change to my diet.

    • evan says:

      Hi Rita,

      Wow that sounds intense!! I’m not doctor and can’t give medical advise. But if I were in your situation, I’d consider decreasing the dosage or maybe trying a different product that has a lower CFU count.

      On their website it says:

      Keybiotics is a super probiotic containing 37.5 Billion CFUs

      In my well researched opinion most people should start out with probiotics in the 5-10 Billion CFU or fewer range. But that is still too much for some people. For example a good friend of mine will get diarrhea for days on end if he has a single 10 billion CFU pill from Culturelle…but I don’t even notice any change when I take the same pill.

      If people are not seeing enough of an effect in that lower dose of probiotics, then they can move up to a much higher does in the 20 – 100 billion CFU range.

      Anyway, good luck to you and feel better!!

  28. Rita Bowman says:

    Is it advisable to continue taking other vitamins and medications while adjusting to probiotics?

    • evan says:

      I think if you took probiotics with antibiotics, then the probiotics would mostly die.

      Other than that, I wouldn’t think it would matter. But it’s best to ask a doctor since I can’t give medical advice!

  29. Dawn says:

    I had the stomach virus 3 days ago. Not up to par but was on my way. I only took one probiotic that was specially made for women. Can one pill cause more symptoms ? Almost feeling worse since taking it. The ones I had bought have to be refrigerated and the reviews were amazing on the brand..

    • evan says:

      Hi Dawn,

      I’m sorry to hear about that stomach virus. Yes, sometimes people can have unfavorable reactions to probiotics. While it is relatively rare, I have a good friend who will get diarrhea for 3 days if he takes a low dose probiotics.

      At the same time, myself and good friends can take high does probiotics and not notice any bad reactions at all. It could be the case that you need to:
      a) try a different probiotic (we’re all different)
      b) need to lower the dosage

      best of luck,
      Evan Jerkunica

  30. Mickie Janney says:

    I am experiencing an outbreak of rosacea, worse case ever and wonder if taking a probiotic for the past few weeks could be the cause. I do know that injections of cortisone I receive every 2 months make my face beet red as does over heating. What do you think?

    • evan says:

      Hi Mickie,

      In my non-doctor, non-medical opinion, I really can’t say. I don’t have any first hand or second hand experience with cortisone. And unfortunately I’m no longer dating my surgeon friend, so I can’t ask her either!

      Here’s what I do know. You can try stopping the probiotics for a week. If when you reintroduce the probiotics you get an outbreak of rosacea again, then the probiotics could be causing the outbreak.

      If you don’t get an outbreak or your symptoms stay roughly the same after reintroduction, then the outbreak likely doesn’t have much to do with the probiotics.

      Take care,
      Evan Jerkunica

  31. Christina Baduria says:

    Hi Evan,

    My daughter is 11 years old and she has severe eczema and very dry skin. When she was born she has eczema after several months the eczema was gone. When she turn 10 year old and she was exposed to pool and sun the eczema came back and it was severe. Can she take culturelle probiotic? Does it help to her eczema?

    She has low positive allergy with dairy and nuts. Thank you
    Hope to hear from you and thank you so much.


  32. Joanne Low says:

    Only my 2nd pill of Florify by Melaleuca and already my tummy has been making so much noise and pain. After 4 rounds in the toilet i felt cleansed and refreshed for my next meal. Is it a normal reaction for faeces to come out black?

    • evan says:

      I don’t think it’s too uncommon, but you should ask your doctor.

      Despite us all being human, our body can behave very differently to the same stimuli…but it’s probably okay if it just happens this once.

  33. RM says:

    Can probiotics cause nausea?

  34. vicky says:

    Hello……I started taking a product called Keybiotics 5 weeks ago for stomach inflammation and it has really helped but Four weeks in I began to develop some constipation. I usually go once a day, at least, and now I am going 4-5 times a week. Can constipation be a valid side effect until my body gets used to this supplement or should I try a diffent probiotic? thanks, Vicky

    • evan says:

      Hey Vicky,

      Glad to hear your’re having some success with the Keybiotics. Yes, constipation can happen as a side effect. And it doesn’t seem impossible that it wouldn’t happen until after 4 weeks of taking it.

      I’d go off them for a while and see if the constipation stays…if the constipation goes away then you can try switching probiotics and see if that gets rid of it.

  35. Beth W. says:

    I am on my 5th Phillips Colon health probiotic pill and I have been dealing with pretty intense nausea. Stomach grumbling, bloating and gas too. I am trying to wait it out!! :-)

  36. Paige says:

    Hi-I am new the probiotic world, and just began taking them 2 days ago. I started the Jarro-Dophilus + FOS…is this a fairly good one to start with? I am only taking 1 pill a day bc I already have a sensitive stomach. But feel like I have had some not so normal cramping and gurgling noises…is this normal? And does it tend to cause lack of appetite/sleeplessness??
    Thank you!!

    • evan says:

      Hi Paige, you are getting pretty typical probiotic side effect symptoms based on what newsletter subscribers report. The sleeplessness is uncommon, but if you have painful cramping then it’s probably hard to sleep. I’d say fewer than 6% of people have side effects at all, but they do happen.

      The probiotics in your body are as unique as your fingerprints, so this might just be how your body reacts to Jarro-Dophilus.

      You can try a different brand of probiotics, you can stop the probiotics or you can see if your body will adjust in time.

      to your health!
      Evan Jerkunica

  37. Jey says:

    I took “Probiotic caps” first two weeks I didn’t get any side effects. The third week I’m having: diarrhea- lot of gas-bloating-cramps-sleepless(I didn’t sleep 2 nights). I went to my physician and she advised to have colonoscopy test. I’m worrying a lot.
    Any suggestion?

    • evan says:

      Hi Jey,

      I am not a medical expert, but if I were you and had your situation I’d just slow down on the probiotics. Or I’d stop them for a week or two. But your situation does not sound too uncommon…sometimes side effects start later.

  38. Bobbie says:

    I have been taking your probiotics for 2 weeks, the last few days my stomach has been feeling tender and gurgly. Now I’ve been very tired and feeling nauseous. Should I back off to every other day and when do I start taking it everyday?

    • evan says:

      Hey Bobbie,

      I’d consider backing off. Maybe take a break for a few days or consider switching to a new brand of probiotics.

      Best of luck,

  39. Ky says:

    I just started using “Culturelle” capsules, 1 per day, and have noticed slight improvement in bowel movement quality.

    However, I might be off, but for reason I am receiving slight discomfort in my right thumb and a little bit in my right wrist and arm today. It’s happened 2 days in a row.

    “Slight Discomfort” referring to nothing painful, not a temperature or even really a circulation issues. Maybe best described as a slight itch or slight heavyness.

    I wish I knew how to treat this, and if in fact the Culturelle is the source. I think I take a day off and see if this symptom stops, and then I’ll know it’s likely from the Culturelle. But if so, that will make 2 treatments that cause deal-breaking side-effects for what may be a mild case of IBS. Levsin being the other I tried and it gave me clear cut case of an inflamed uvula.

    Other than a religious consumption of water and high fiber diet, or possibly a different probiotic like Allign, which my doctor suggested, I’m kind of back at square one with treating a potential case of IBS.

    Any thoughts/advice?

    • evan says:

      I haven’t heard of joint stiffness being a side effect, but I could imagine it happening if your detox systems are stressed out. Then the potential bad bacteria die-off could overwhelm your detox and cause such symptoms.

      Culturelle has one strain of probiotics. If I were in your situation with IBS I’d opt for a multistrain probiotic. Our body needs 500+ different bacteria so I think a shotgun approach is better. You can find one here:

      I would also be careful with the idea of high-fiber diet as being gospel. If it makes you feel better, than do it. But also try lowering the fiber as well.

      If I had IBS I would focus on:
      a) lowering stress
      b) getting 8+ hours of sleep every night
      c) bedtime no later than 10pm
      d) mild to moderate exercise every day…we gotta move!
      e) eating food that you can digest well
      f) taking digestive enzymes if you don’t digest your food well

      I think the biggest challenge with IBS type issues is that they follow a downward spiral. You digestion gets compromised, then you need more nutrients to heal, but you can’t absorb them, then over time as people become more and more nutrient deficient, then the problem gets worse.

      So please work to improve it now. Go find things that are easy to digest, rest up all you can, and make time to chill out.

      I wish you the best,
      Evan Jerkunica

  40. Sharon Pinsley says:

    What about cystitis?!

    • evan says:

      Hi Sharon,

      For everyone else cystitis is essentially a urinary tract infection (UTI).

      I haven’t heard of this but it could very well happen. This could be a rare side effect.

      I hope you feel better!
      Evan Jerkunica

  41. Robert Williams says:

    I started taking “Trubiotics” two weeks ago and I went through the gas, loose stool, bloated stage. This lasted about nine days and then it was over. I am on a diet (1200 Cal.) and my cravings for carbs has nearly been eliminated since I started taking the probiotics. I do have one question about constipation, I haven’t had a bowel movement in three days. It started just after the gas explosions quit and was wondering if this was common with taking probiotics? I don’t feel bloated and my diet is mostly protien from fish.

    • evan says:

      Hey Robert,

      Yes this type of side effect can happen for some people…though your symptoms sound on the extreme end of the spectrum.

      I’d say not having a bowel movement for 3 days is not good. A healthy digestive track moves 1-3 times a day, pushing out about 12 inches total each day.

      If I were in your situation I’d probably tweak my diet a bit more. I’d also consider taking a few days off the probiotics & seeing how that feels.

      to your health,
      Evan Jerkunica

  42. Tristan says:

    I started taking Keybiotics about 5 days ago and my first few days were great but after that it has been a horrible experience, hot and cold flashes, nausea, dizzy, aches and pains, lower back soreness, sore throat, ears are stuffy, very lethargic and all that jazz. I am used to taking a 8 billion probiotic from NOW foods and the only thing I can think of is that this is much stronger and much more resiliant so i am getting a lot more active cultures in me. I have decided to drop to 1 pill every other day to help with the sysmptoms and get my system used to the CFU’s

    • evan says:

      Hey Tristan,

      Good – yes lay off it a bit. Maybe once every 3 days could be right for you.

      Or maybe switch back to your old probiotic – yikes.

      feel better,
      Evan Jerkunica

  43. mandy says:

    I had a colonic irrigation on Thursday and was advised to take forever active probiotic capsules, 2 capsules per day one am before or after food and one pm before I go to bed. Advised to take that dose for 5 days and then reduce to 1 day. as supply has 30 tablets, I had been bloated and belching before I took the capsules and had the colonic. Since I have been taking these capsules. I am still belching throughout the day and feel a bit sick, my skin has come up in a rash on my cheeks and chin also back.At nights I feel really hungry like I want something to eat but I am no longer bloated. Any thoughts on this please

    • evan says:

      Hi Mandy,

      I had a round of 3 colonic irrigation in 6 weeks. I had some serious detox symptoms and I felt angry all the time for about 3 weeks after the last colonic.

      I would make sure you take it really easy and relax – that’s a good way to deal with these side effects.

      Definitely stay hydrated, and also consider taking a break from the probiotics. Our bodies can only handle so much at one time.

      Listen to your body’s signals, feel what’s right and do it. Stop doing what other people tell you to do!

      to your health,
      Evan Jerkunica

  44. Cathie says:

    Hey, anyone else having an issue with sour saliva after taking probiotics for a couple weeks?

  45. Craig says:

    Hi Evan, just starting taking Neways Protozymes as recommended by my doc 10 days ago.
    Starting taking 2 pills per day and experienced serious bathroom sprint sessions.
    dropped to one pill per day and only showing slight improvement – no more sprinting but still VERY loose movements.
    Now have sore throat and ears – linked or coincidence?
    middle of the fence currently – persevere with the pills or pack them in.

    thoughts/ comments??


    • evan says:

      Hi Craig,

      I have good news for you!! It’s very likely your probiotics are working.

      Those are very common adverse effects…sore throat/ears, loose bowel movements, etc. are often signs of the new probiotics fighting and killing the bad bacteria. So really those are typically side effects of detoxification, rather than side effects of the probiotics directly.

      I’m not your doctor, but you can consider going down to 1 pill every other day and seeing how that works. Be sure to rest up, eat healthy food and maximize your body’s detoxification pathways.

      take care,
      Evan Jerkunica

  46. Sara says:

    Have taking probiotics for 3 weeks and now have terrible diarrhea and lots of bloating and gurgling in my stomach .this is not fun so I quit taking them I can’t even leave the bathroom .

    • evan says:

      Hi Sara,

      Yes, these types of side effects can happen. If you follow the directions above (reduce dosage, increase rest), you will likely have a better outcome next time.

      Evan Jerkunica

  47. Mary says:

    I just took Primal Defense. My candida has gotten worse over the years and I am unable to work. I just started the diet. My question is the first day of taking Primal Defense (I took one pill), I had gurgling in my stomach. The second day, I decided to do two pills. One in the morning and another in the evening. Weird thing happened, my skin, eyes, tongue, everywhere, I was itching. Is this part of die-off? It’s a brand new bottle and expensive. Has anyone else had this problem? Thanks

    • evan says:

      Hi Mary,

      This is a very common detox reaction. I’d consider dropping down to 1 pill every other day and build up from there. Cool?

      Evan Jerkunica

  48. Kim says:

    I had my gallbladder removed in Nov and have had problems ever since. Fiber enriched foods give me gas and i have chronic constipation. I had a colonoscopy a few days ago and the results were fine. Everything i eat seems to give me gas. I know i need fiber to help with the constipation but my system is not digesting foods very well. I eat bland foods with a lot of baked fish. My GI doctor just gave me samples of Lizzness and Restora probiotic. Have you heard any good reviews in reference to Restora.

    • evan says:

      Hi Kim,

      It sounds like you’re accustomed to experimenting with your diet to find what works. I would do the same with probiotics.

      Best of luck,
      Evan Jerkunica

  49. Janice says:

    I’ve had my gallbladder removed 12 years ago and are experiencing acid reflux and are taking omeprazole now daily and have taken a series of antibiotics over some years, would you consider taking probiotics at this time thanks janice. Ps I can’t eat anything acidic

    • evan says:

      Hey Janice,

      I’m not a doctor, but ideally you could work with a doctor who knows about probiotics and can advise you there.

      But I I were in your situation, I’d take a low dose probiotic a work up from there. Try something like 1-10 billion or so and see how that goes.

      best of luck,

  50. Laz says:

    I took 50 billion probiotic (yogurt) from bioK for 6 days.
    On the 7th day my stomach was bloated and gassy. I also got mild diarrhea for 2 days now. Are these normal side affects?

    • evan says:

      Hi Laz,

      Yes, this is a very common side effect. You can choose to push through it, or back off a bit on the probiotics. It’s up to you and what feels right.

      to your health,
      Evan Jerkunica

  51. Louis says:

    I took probiotics for 1 week. Then I starred to feel very bloated and got minor diarrhea. How long should the diarrhea and gas last after I stop taking the probiotics.

    • evan says:

      Hi Louis,

      It depends. Our bodies are all very different.

      If you have already stopped taking the supplement, then you’ll probably just have to ride out the side effects.

      Evan Jerkunica

  52. Susan says:

    I have beautiful skin normally until I started Keybiotics. From the back of my neck, shoulders, my back, forearms, stomach, legs,and hands. I even saw a few spots on my butt but my hands and forearms are the worst. Is this normal? I am, however, going to the bathroom without having to take all those other pills like senna with laxative and I feel like a normal person, again. But this itching is driving me nuts. I have had oatmeal baths, white vinegar baths, baking soda baths, and I even tried apple cider vinegar because it takes the swelling down. I started on the Keybiotics March 22nd and I am 66 years old with hay fever (have had all my life). I only take one pill in the morning and cannot take dairy products, soy, gluten, or wheat. All of that resulted from stomach surgery. Is there another Probiotic that works without all this itching and my skin looking terrible? Really need some advice here. Thanks! Otherwise, I am going naturally…thank God.

    • evan says:

      Hi Susan,

      Many people come to this page complaining about severe Keybiotics side effects. So this could be 1) they have a very strong dose or 2) they have non-optimum strains or 3) they have something in there that people could be reacting to. It’s probably the case that they are relatively strong, but they haven’t responding to any of my inquires to them so I don’t really know if it’s questionable ingredients or sub-optimum strains.

      Assuming that Keybiotics are just relatively strong, then here’s what I have to say.

      When you take probiotics, often times initially there is a spike in chemicals that need to be detoxed from our body. This is because when the probiotics kill the bad bacteria, our body needs to “take our the garbage”. And in this case the “garbage” is the bad dead bacteria.

      For many people, part of that detoxification is our body pushing out those chemicals through our skin. Since our old skin layers are constantly being shed, this is a decent way for our body to detox. For others it could be very smelly sweat or urine. For me personally, I will get mild to severe dandruff if my body wants to detox.

      You can try and reduce the dosage (eg. every other day), rest more, de-stress, and have some light exercise and see if that helps.

      If you’re done with keybiotics and want to try something else, you can use our Personalized Probiotic Finder to find your something that may suit you better.

      feel better,
      Evan Jerkunica

  53. Brenda says:

    I have all those symptoms except acmne. Also feel VERY weak and a little dizzy. Only drinking a sm glass a day for the past week. Is this normal

    • evan says:

      Hey Brenda,

      These are typical side effects…though weak/dizzy is not as common.

      Maybe drink only 1/2 a small glass? Or take a week or two off from the probiotics?

      best of luck,
      Evan Jerkunica

  54. Winston says:

    Have a ulcer in stomach, bloated stomach, stool stick to toilet regularly and is dark. Started 50 B probiotic supplement can a change in stool color indicate probiotic working

    • evan says:

      Hi Winston,

      Yes a stool color change can indicate that the probiotics are changing your inner environment. However, a change in stool color can also come from different food or even different levels of colon hydration.

      I personally believe that a change to bowel movement regularity/firmness/quantity are stronger signs that the probiotic is working..

      to your health,
      Evan Jerkunica

  55. dave says:

    Can children under 13 years old use keybiotics?
    Thank you, you’ve been a big help.

    • evan says:

      Hi Dave,

      I am not a doctor, but I’d use Keybiotics sparingly with someone so young. It should be okay though…just go slow!

      to your family’s health,
      Evan Jerkunica

  56. Claire says:

    This is my first experience with probiotics. I am using Mercola’s and don’t know which are the best. I felt an improvement in my mood, but felt also pain in my hands and fingers sort like an arthritic pain. Also I am unable to sleep as I used to. Is this normal? I would definitely appreciate your input.

    Is this normal.

    • evan says:

      Hi Claire,

      This is not an uncommon side effect of probiotics. When probiotics go and fight the bad bacteria, many toxins can be released. Slight arthritic-type pain can be a symptom of your body being over-burdened with toxins…and the same with sleep issues.

      If I were you I’d make sure to drink plenty of water, consider tapering down the dosage and seeing what happens.

      I’ll be making a video on detoxification tips very soon!!

      Evan Jerkunica

  57. debby collins says:

    Does probiotics cause rash on chest and stomach?

    • evan says:

      Hi Debby,

      Yes, this can happen very often.

      Follow the steps above and you’ll likely feel better in no time :)

      Evan Jerkunica

  58. Celia says:

    I started using Keyboticts 7 weeks ago and for the last 5 days my urine odor has changed, will probotics harm the kidneys?

    • evan says:

      Hey Celia,

      I’m not aware of any research that probiotics will directly harm your kidneys.

      Now this is speculation, but indirectly, it is very possible that probiotics could increase load on your kidneys. They could increase the waste products in your blood, which then needs to be filtered, which would add new/more things to your urine.

      take care,
      Evan Jerkunica

  59. Joyce says:

    I’ve been fighting shingles now for 6 weeks and I’m still suffering from pain where the shingles blisters were located. I started 15 billion probiotics midway thru this and was feeling better. I was taking 5 billion 3 times a day. A friend coaxed me to bump it up to 20 billion. So I did this and by the 3rd day I had a rash all over my head. I’ve since stopped and the rash has gone away. I really want to go back on it, but now I’m stuck with 20 billion capsules. Any ideas on breaking these capsules in half to take half in the morning then again at night? Or should I wait til after this shingle pain goes away? I’m sure I’m in toxic overload with having fibromyalgia and type 2 diabetes. What would u suggest I do? Thank you.

    • evan says:

      Hi Joyce,

      I would definitely try splitting the 20 billion capsules in two – you should get a much lower does that way.

      Experiment with it, and hopefully you can get back to your original routine and feel better soon.

      take care,
      Evan Jerkunica

  60. Lou says:

    This is what I am experiencing right now: sore throat and congested ears with heaviness of the head. Just like what Rob said he experience. I am also constipated for two days now. I found your article and now I started drinking plenty of fluid and lower the dosage of my probiotics to only one capsule a day. I hope these side effects will go away.

    • evan says:

      Hey Lou,

      Thank you for the comment.

      Don’t be afraid to reduce the dosage as much as you need to – even taking a probiotic once every 3 days is a great starting point.

      You can eventually work up to the “normal” dosage :)


  61. Priscilla Pillsbury says:

    I recently came off of Align after several years,
    feeling I was posssibly becoming “immune”-
    I then tried Digestive Advantage, then Philips which made me quite ill, and now am
    on Culturelle which immediately made my stomach feel better but also seemed to constipate me. Is it harmful to switch strains of probiotics
    and do you indeed become immune after years?

    • evan says:

      Hi Priscilla,

      I don’t have scientific research to support this opinion, but I do believe our body can have “enough” of a probiotic…and that after a while it won’t do anything for us.

      I think it’s a great idea to:
      a) rotate probiotic brands
      b) rest from probiotics completely for a time (say 3 months on, 1 month off)

      Because while supplements are often a good thing, we need to let our body do it’s own thing and adjust.

      That is what works for me, so maybe it will work for you.

      to feeling great,
      Evan Jerkunica

  62. Darleen NcCorchuk says:

    I’m 56 in great health except IBS. I can barely eat because I always feel full, bloated and uncomfortable.
    Went to a gastroneurologist and she put me on Miralax once a day and Align probiotic two times a day. The dosage on the bottle says to take once a day. Is it ok to take Align twice a day? This is my second day and I don’t feel any better. Sounds like it takes awhile.
    Any advice?

    • evan says:

      Hi Darleen,

      If you aren’t feeling anything within the first week, then I would consider:
      a) increasing the dosage
      b) trying a different probiotic — since Align only has one strain (B. Infantis), then your body many need a different strain to “get things moving”.

      take care,
      Evan Jerkunica

  63. Brent peterson says:

    Jumped from 60billion to 100billion probiotic. Within 4 days, heavy anxiety; within a week, heavy brain fog and head pain. However, anxiety and fog are ongoing symptoms (pre probiotics) for me. How to tell if it’s die off or regular symptoms? Seems more intense with probiotics.

    • evan says:

      Hi Brent,

      It is not easy to say which comes from what.

      But with any powerful medicine like probiotics, medical drugs or strong herbs, you body will have an increased detox load.

      In my non-medical opinion the brain-fog type symptoms are associated with an overloaded detox system, so taking probiotics could make things worse for a while.

      I’d consider dropping the probiotic dosage back down to what it was and also finding a way to improve detox…doing light exercise + removing any junk food from your diet are a great start.

      take care,
      Evan Jerkunica

  64. eileen says:

    I just recently took Ohhira Probiotics and developed spot rashes on my arms and upper body. I read the article that it’s the body detoxing. Should I stop or continue taking the supplements? I do have history of eczema and lactose intolerance. Many thanks!

    • evan says:

      Hi Eileen,

      Generally when probiotic side effects happen you need to:
      a) lower dosage or frequency
      b) rest more
      c) drink lots of fluids

      best of luck,
      Evan Jerkunica

  65. U & J says:

    I’m caregiver for my 90 year old dad and have just learned about probiotics. Should I just start him (and myself) on one pill every 3 days?…, because I certainly don’t want him to have to run to the bathroom, you know… ever… ;)
    I don’t know if he has candida, but he loves anything with sugar in it and until last month I would get him those sugary oatmeal cookies and chocolate, and things he loves. He also seems to NEED or crave sweet cole slaw. But now I’ve just learned about soybean products and high fructose corn syrup that is in EVERYTHING I’ve been buying for him. High fructose causes brain fog and dementia/alzheimers conditions… and the cole slaw I was buying at the store has high fructose corn syrups and other sweet junk in it. .Soy products destroy the thryoid! He has low thyroid, and low hemoglobin, and such as that shows up in his blood work, and his Dr found a 2″x 2″ mass in his lungs. He went for the first CT scan, but decided there is nothing wrong with him and he will not let them dig into his body and upset his life. but he is healthy, doesn’t take a single pill, takes a walk every day and eats well, goes to sleep around 6:30pm and wakes up around 7am.. and naps all day… but he hates water. Also says his bowel movements are normally only once every other day. But I’ve noticed many times that it’s many times every 3 days. He forgets by the time he comes out of the bathroom, whether he had one or not ;).
    I’ve researcched and learned that if it’s cancer in his lungs, cancer feeds on sugar, but since we didn’t let them scope it out, it could be mold, (since we do have some plumbing problems). He doesn’t want to go through all the doctors recommended and let them ruin his life because he says he is just fine. I applaud that. We are proud of our natural cures and no doctor approach to a pretty pain free life.
    I found a place to buy Xylitol instead of sugar and he can’t tell the difference, but since he isn’t over weight, taking away the sugar made him start to lose weight. I’ve started making his cole slaw at home, using cinnamon and apples coconut oil and a spoon of coconut sugar in it to sweeten it. I’ve started making his oatmeal from organic rolled oats and instead of sugar I use coconut sugar. I’m making his oatmeal cookies too, with banana, coconut oil, flak seeds and all kinds of good for you stuff in them. I’ve just learned that Mayonnaise is filled with soybean oil and so now I’m making my own mayonnaise. Only since March 2014, did I decide to not let him consume anything with high fructose or soy products in them, and after about 3 weeks, he wasn’t feeling too good either. I wondered if he was going through withdrawal.
    My question is about sugars as well as probiotics. We hate stevia, but Xylitol tastes just like sugar, and coconut sugar isn’t bad either. Do these other natural sweeteners do the same as sugar or are they OK to sweeten his green tea with, and my coffee with? And how can I keep him from losing weight if I take away sugar? Just this week, I mixed his sugar bowl with the three sugars. Refined sugar, coconut sugar and Xylitol to try and keep him from losing weight. Please comment on this, Thank you so much for this forum and the way you answer. I am so glad I read it, because the way I learned about probiotics was through the Keybiotics ad online. It is expensive but I was sold on it. However, then I saw another one being offered at one of my health food shops online, much cheaper, so now I’d like to get one for sure, but I wondered if it’s dangerous for the elderly to take. Sorry this is so long, I think I only asked a few questions, though. I’d love your advice, please. Thanks again!

  66. Cherylpatnaik says:

    Taking probiotics for several months, once a day but
    Am having problem with rectal mucus discharge. Could the probiotic be a problem?

    • evan says:

      Hi there,

      Possibly – you can try going off the probiotics and seeing if it gets better. But there are many many causes of this issue, go ask a doctor for the full list…likely many having to do with dehydration.


  67. Diana Levitt says:

    When starting off what is considered a recommended low dosage?

    • evan says:

      Hi Diana,

      Personally I think 5-10 Billion is a great starting dose, but it will vary per person. If I were new to probiotics I would take 5 billion, wait 2 days and then try another 5 billion. Then I would try 5 billion every day, then I’d take 2x 5 billion probiotic pills after that.

      Slow and steady :)

      I’m actually considering working on a very clean, low dose starter probiotic with minimal side effects for this exact reason.

      to feeling great,
      Evan Jerkunica

  68. Alison Spenst says:

    I started taking Culturelle probiotics 5 days ago, I do have a rash in and around my belly button followed by a weird smell….is that part of the detoxification?

  69. Alison Spenst says:

    Sorry forgot to ask , also I woke up this morning n my left eye is irritated n sore a bit, is this a side affect as well? AND since I am coming on day 6…should I stop taking them or ride it out. I was recently sick and all the meds the doctor had me on cleaned out all the good bacteria in me, reason why they now have me taking probiotics is to build back up the bacteria.

    • evan says:

      Hi Alison,

      That may or may not be related to probiotic side effects.

      But it may help to lower the dosage – take the supplement every other day, or something like that.

      Evan Jerkunica

  70. Alyeska says:

    Every probiotic I’ve tried has caused me bloating, gas, and cramps :( I’m very frustrated because I believe they are so good for health. I recently tried 10 billion L. plantarum and it was too much for me. Is eating fermented food/drinks a good substitute? I seem to tolerate kombucha okay.

    • evan says:

      Hi Alyeska,

      I’m sorry to hear that :(

      Have you tried a fermented drink like kombucha or water kefir? Or un-pasteurized sauerkraut? Those are generally much less concentrated than the supplements.

      feel better,
      Evan Jerkunica

  71. Mindy says:

    Can probiotics make my one year olds urine smell foul? I started giving it to her about 2 weeks ago after a few rounds of antibiotics and a lot of diarrhea but now her urine is so foul smelling. No fever or anything so I don’t think its a UTI. Thanks.

    • evan says:

      Hi Mindy,

      I have heard of this happening to other people.

      You can take her off the probiotics and see if it stops, or continue taking the probiotics and see if it goes away on its own.

      I wish your daughter well,
      Evan Jerkunica

  72. Martha says:

    I ache all over…that a side effect?

    • evan says:

      Hi Martha,

      Yes, flu-like symptoms can be an side effect.

      If it’s too much or doesn’t go away for a few days, I would stop the probiotics and potentially slowly ramp up the probiotics dose next time you try them.

      Evan Jerkunica

  73. U & J says:

    So, if one prefers not to take the supplements, what is the best natural way to go? Is there a diet to go by, like eating sauerkraut every day for a month or maybe just ingesting some fermented food or drink each day? How much? and for how long? Is there a way to get that bacteria back in balance naturally? Since you offered no advice we decided to not buy the probiotic products, due to his age. You also didn’t answer the question about sugar, coconut sugar, xylitol. Do these alternative sugars feed the parasite as well? And how about honey? Thanks

  74. Jackey says:

    Usually been taking probiotic with no issues. Just recently introduced to Epoca Cool+ that CostCo has and after 4 days I’m having mild fever chills and nausea. I’ve been popping my regular Probiotic pills plus Epoca Cool+ twice a day. I was thinking what did I introduce to my diet and this is the only new thing on my diet since past week. They have it for about entire pack for just 10 bucks whereas the one I was/am taking in pill form is more expensive. I think this new probiotic is extremely inferior or probably infected with wrong bacteria that I’m having these issues with and their plastic container looks cheap and dirty. I doubt if it’s BPA free and that solution is highly acidic too with Vitamin C in plastic container.
    I don’t believe in die-off symptoms. It’s just self-consoling ideas which is okay. A good probiotic never causes so called die-off where as bad probiotic causes so much problems. I’m gonna call Epoca Cool+ manufacturer today and see what they say. Will update later.

    • evan says:

      Hey Jackey,

      While it’s possible that the product is contaminated, it is probably very unlikely.

      Our bodies are very unique and sometimes a probiotic can cause large changes in our body…even at low doses.

      Either way I’d just keep using the one probiotic that is working for you, or I’d stop your regular probiotic and use the new one exclusively.

      As far as a good probiotic and a bad probiotic goes, I believe it is like food…I lost about 25 lbs when I was eating a high fat/protein diet. But when my ex girlfriend ate the same way as I did, she would gain weight!!

      Don’t believe what people say – in many ways you are as unique as a snowflake! Don’t be afraid to experiment and try new things, even if it’s a disaster like what you described above.

      take care,
      Evan Jerunica

  75. Luie says:

    I just started probiotics today for the first time 1 pill after meal. I read many side effects good and bad so I will play it day by day and will post any good or bad results. great job in answering questions !

  76. rudedude says:

    Your comments was helpful. Thank you

    • evan says:

      You’re very welcome.

      But you should really thank all the brave commenters on this page, they are very brave to share this information!

  77. Marianne says:

    Started Jarro-Dophilus only a couple days ago, and I’ve broke out in a horrible rash that just hurts. As long as I leave it alone the rash don’t itch, but it hurts. I have eczema and this seems to have made it far worse.

    • evan says:


      I am so sorry :/

      Although it’s not working for you now, there is strong evidence that probiotics help with eczema.

      Once the rash calms down I would try some non-sugary fermented food like Kimchi or sauerkraut.

      feel better,
      Evan Jerkunica

  78. susan says:

    Can probiotics help with alopecia??

  79. Brooke says:

    Hi this might be TMI but I just started taking hyperbiotics and it’s seemed to give me a yeast infection, is this a normal side effect?? Does it mean the hyperbiotics are cleaning out my system? Thanks

    • evan says:

      Hi Brooke,

      It could be. I would stop the hyperbiotics for a week+ and see if the yeast infection goes away.

      As you can read in the comments above, there are 101 different possible side effects for probiotics.

      Evan Jerkunica

  80. Jennifer says:

    Thank you! I was concerned I may have improperly fermented my vegetables. I have always been one to jump in head first, and having dealt with Candida for many years, I was so excited to get well that I clearly over did it! I cut back and saw immediate relief.

  81. Chels says:

    Hey Evan,
    Been doing lots of research on/taking probiotics. I have been suffering from bv, yeast and uti’s since stopping birth control pills about a year ago. Now I am pregnant and wanting to try to make sure I’m as healthy as can be. A nutritionist recommended Garden of Life raw vaginal probiotics 50 billion. I took one capsule along with my prenatal vitamin before bed and woke up about 5 hours later extremely nauseas, heart racing, had loose stool and skin very hot. I know it’s a reaction to the probiotic but I don’t know if I should just stop using it or take half a pill..maybe with food in the morning?
    Any advice? Thanks!!

    • evan says:

      Hi Chels,

      I’m not a doctor, but I would stop taking them for the moment. Wait a week, then try a 1/2 pill.

      See how you react then – if you feel okay, do 1/2 a pill for a few weeks, then try 1 pill.

      take care,
      Evan Jerkunica

  82. Jayne peters says:

    Been taking probiotics for 2 days, increased dosage as suggested by retailer when purchased, to 4 a day as stomach was so painful, bloated, acid reflux. Now got diarrhoea. Hope its just getting rid of the rubbish for taking too many medications over 4 years! When should I stop if it doesn’t cease?

    • evan says:

      Hey Jayne,

      I’d go down to zero pills per day. After your feel normal again, then start with 1 pill every other day. You can increase the dose as you feel ready.

      Yes – 4 years of medications will royally screw up your flora.

      feel better,
      Evan Jerkunica

  83. Rachèl says:

    Hi Evan,
    very helpful thanks! i’ve been taking two capsules of 3 billion a day and willprobably cut down to one daily. i’ve beenlosing my appetite and feeling bloated also i feel very tired as well as agitated.
    this is my first round taking probiotics. as a child i used to have astma, eczema and bronchitis for which i was perscribed large doses of antibiotics. is it possible that my tiredness and agitation come from cleaning up years of bad intestine flora?

    • evan says:

      Hey Rachèl,

      If the probiotic supplement is the only thing you’ve changed, then the re-balancing of your probiotic flora could be causing the side effects. The best way to find out is to reduce the dose or stop taking the probiotics for a week or two.

      I wish you the best,
      Evan Jerkunica

  84. Heather says:

    Can taking a probiotic help with gluten sensitivity? I’ve had constant diarrhea for the past almost 4 years now. I had my gallbladder removed, and that didn’t help. I took the suggestion of a friend and eliminated gluten from my diet, and that took care of about 80% of the problem, now it’s only every couple of weeks. So I started taking a probiotic, it’s been 4 days now and I’m getting some of these symptoms, glad it’s from the detox, but I was wondering if I’ll be able to eat bread again in the future. Thank you.

    • evan says:

      Hi Heather,

      Please keep in mind I’m not a doctor when you’re reading the rest of this.

      It depends. If this is an intolerance that recently developed, then by getting your digestive vitality back could reduce/eliminate your sensitivity. But that would take serious dedication and work, especially with your gall bladder removed.

      I have anecdotally heard that people with gall bladder issues greatly benefit by taking gall bladder salts. Consider finding a high quality gallbladder bile salts supplement. Honestly this is something you’ll have to research since I am not very familiar with this topic.

      happy healing,
      Evan Jerkunica

  85. Kitty says:

    Thank you so much for this. I was really starting to worry something was wrong. I’ve taken probiotics before but was (unbeknownst to me) storing them incorrectly therefore consuming dad probiotics. I just started a fsh strain two days ago twice daily and a already feeling the effects. Will be reducing to ine until they subside.
    Thank you again !!!!

  86. Melissa says:

    I think this article made me feel better about what’s going on with me. I read a lot of the comments and your replies, but tell me if you think this is common. I increased my dosage from 15 billion to 30 billion (took 15 billion forever then one day began taking 30). After a few days I had diarrhea for a few days then began having normal bowel movements 1-3 times per day which is an increase from 1-2 times per week for me. I felt GREAT and was totally loving this 30 billion. Then about 6 weeks in I began having burning pain in my upper abdomen with diarrhea for about four days. All I could eat was rice. Today is the 7th day since that began and certain foods literally shut me down. I have to go take a nap and I have the terrible burning pain with a few loose bowel movements. When I wake up, I’m totally fine like nothing ever happened. I’ve lost 10 pounds in 7 weeks which is fine with me. I felt GREAT before this week long bout of weirdness! I also have had some headaches, skin itchiness, and I’m so tired. Could this all be detox symptoms in your non medical opinion (which I prefer by the way – don’t get me started on why)?

    • evan says:

      Hi Melissa,

      I’m glad you had some great results, but these recent side effects sound terrible!!

      I would go off the probiotics for 2 weeks and see if things improve. Then if that doesn’t work, go back on the 15 billion and see if that gets your back to normal. If things still don’t go back to normal, I’d look into lifestyle factors like sleep, stress, hydration, etc.

      Please be very careful with rapid weight loss – 10 lbs in 7 weeks isn’t too much…but if you drop 10 lbs in 1 week, I’d seek medical attention.

      happy recovery,
      Evan Jerkunica

  87. G Shanti says:

    I have a couple of questions regarding probiotics.
    1) Since the are reports of special strains of bacteria in people who eat special foods (seaweed for example), I would imagine that the ideal gut bacterial colony for your gut depends on your diet. If yes, are there studies that have attempted to look at what is the right colony for which diet?
    2) One would imagine that if you take a probiotic for a certain number of days you would be able to establish a stable colony of the bacteria in your gut and that overpopulating the gut with that bacteria could potentially be problematic. What then is the rationale for manufacturers recommending lifelong supplementation? Are there issues with the strains marketed? or is this just business trumping science?


    PS: I would prefer honest answers to the above, or none :-)

    • evan says:

      Hey G Shanti,

      We only have honest answers here!

      1) The food you eat will feed some probiotics, and starve others. Therefore your probiotic colonies will adjust their population to match your diet.

      2) The rationale is that manufactures want a lifelong customer. You are 100% correct that it is possible to over-supplement one type of probiotic…and that will give you wrong mix of probiotics!

      You should take one product no more than 3 months at a time…then switch to a different one.

      very insightful questions,
      Evan Jerkunica

  88. Mera says:

    I had a pretty violent reaction to my first 5 days of “extra strength” probiotics. It triggered the worse IBS episode I ever had, complete with chills and a fever that clocked in at 101.3 and lasted about 18 hours. I couldn’t sleep b/c I was awakened every hour to relieve myself. When the fever went away, I was left with passing mucus alone, and mucus with stool. I stopped taking it. LESSON: I probably began with too high a concentration and should have begun on the bottom rung. Will try again with a lower “dosage” when this bout of IBS goes away because I won’t tolerate these side effects.

    • evan says:

      Hey Mera,

      Yup – this is challenge. Many people want to jump right in with the best/strongest, but some people can experience side effects.

      best of luck,
      Evan Jerkunica

  89. Hadi says:

    Hello. Is it normal for probiotics to cause dizziness?

    • evan says:

      Hi Hadi,

      No. I would go see a doctor about that.

      For me personally, I can get dizzy if I don’t have sufficient electrolytes.

      feel better,
      Evan Jerkunica

  90. Anton says:

    Got a stomach virus 2 weeks ago. Advised by doc to take florastor probiotic. Had loss of appettite, fatigue, weightloss, gas, insomnia. Is this normal?

    • evan says:

      Hey Anton,

      How long has it been going on? Rapid weight loss can be a symptom of very serious conditions. Please go see your doctor again for a check-up and see if going off the probiotics helps.

      Evan Jerkunica

  91. Norma says:

    Loose stool is normal when we eat too much of anything . Is a good thing that a loose stool lets you know you are taking more then you need is need it :) God bless you all .

  92. Norma says:

    My son had dandruff I gave him probiotics and he is so much better :) his hair is not falling out :) God is good !

  93. Anton says:

    About 2-3 weeks. I have a gastro appointment tomorrow and a sleep study tomorrow night. Ive also have been dealing with stress and anxiety. All so overwhelming. ..

  94. Aaina says:

    I took a 50 billion dose of probiotic 2 days ago. For two days, I have been constipated, very bloated and nausious. Today I ate prunes, and I have been experiencing intense diarhea for half a day now and grumbling noises in my stomach. My nutritionist said to decrease the dose but still continue- but should I be? It’s a pretty uncomfortable experience so far.

    • evan says:

      Hi Aaina,

      If I were personally in that situation I would consider stopping the probiotics for a few days…or just taking them only every few days.

      Once your body has gotten used to the dosage, then you can start increasing the dosage or start taking the probiotics evey day.

      feel better,
      Evan Jerkunica

  95. Deborah Johnson says:

    I just started taking Restora, given to me by my doctor. So far, so good, except, about 30 minutes after taking it I am getting a headache and some nausea. Is this normal. I am really not a headache person so this is a little troubling. Other than that, I am very pleased and intend to continue. My other symptoms have really normalized. I am a happy camper.

    • evan says:

      Hi Deborah,

      Typically probiotics aren’t going to cause that sort of side effect that quickly. Did it possibly get stuck on the way down as you were swallowing?

      glad you’re feeling better,
      Evan Jerkunica

  96. Judy says:

    Have been taking probiotics for a few days and the directions said take (2) if you are having stomach upset and diarrhea so I did. Bad case of diarrhea today, not sure if I should quit already of just cut back to one.

    • evan says:

      Hey Judy,

      You can quit the supplement to give your body a break. Once your body goes back to normal, you can start taking the probiotics at as low a dose as possible..say every other day or as few pills as possible.

      Evan Jerkunica

  97. chris says:

    Started taken them last week on the 13th by the 15th the bloating the gas the pain still going on and it’s the 22nd you can see the bloating all day long I go to sleep fine then in the morning take 2 then it begins take 2 more not to realize that this may be the probiotic till i started doing research,to fine out this can happen. Well I’m going to stop taking them to see if the bloating goes away and the pain and gas.
    even went to my dr she thinks I need to see a GI dr they don’t talk about the problems that can occur but i will see if this is the reason.
    Does anyone kn ow once you stop taking the probiotic how soon you feel better I want to be able to eat Christmas dinner and feel fine and not want to go to the hospital my last does was 3pm today took 2 and earlier in the morning took 2

    • evan says:

      Hi Chris,

      If the side effects are too intense you need to either:
      a) decrease the probiotic dosage
      b) stop taking the supplement all together

      feel better Chris,
      Evan Jerkunica

  98. Manda says:

    For the author of this article,

    Now I have a complete understanding on my Probiotics Eleven I’m taking daily. I’ve been trying to figure out which of my natural suppliments have been causing me to be constipated for a long time, and of the three natural suppliments, it’s my Probiotics Eleven. I think its also because I’m also taking 3 different types of anti depressants and birth control is why I’ve been very constipated. I wasn’t having bm issues this bad until I added my natural suppliments to my prescribed medications. I was recommended Probiotics Eleven by a naturalist that owns his own herbal store for my sinus and ear infection, as well as Olive Leaf Extract and Magnesium. I’ve only been taking them for 3 weeks now as recommended, but being constipated and bloated is not fun for me. Will I continue with constipation and bloating after my first bottle usage is gone? Or will I go back to “normal” when I buy a second bottle?

    • evan says:

      Hi Manda,

      That is a pretty complicated mix of supplements. Can you work with your doctor to maybe swap out some supplements that aren’t as necessary? Then you can see what will make the constipation go away.

      Evan Jerkunica

  99. Tia says:

    Can very strong probiotics be given to children? Is 50 billion or 100 billion too much for a child if they are experiencing severe issues like eczema and gut problems?

    • evan says:

      Hi Tia,

      I would consult a doctor. But if they were my child, I would start very slowly.

      I would try 1/2 a pill, every other day and see how that worked. If that dosage was fine, then I would increase the dosage from there.

      feel better,
      Evan Jerkunica

  100. Chris says:

    Hi I have been on antibiotics for at least 6 of the last 8 months for ear infections. Also I have been given at least 4 rocephlin shots. Now I am severely constipated. I started taking the Multidophilus 12 Strains Enterically Coated (taking 4 capsules a day). I still have not had any movement. Please Advise

    • evan says:

      Hi Chris,

      There are a number of ways to get your bowels moving. Here’s what I would do if I were you:

      • Have you tried drinking more water?
      • Have you tried going on a walk?
      • Have you tried doing squats?
      • Have you tried yoga?
      • Have you tried massaging your intestines?
      • Have you tried a squatty potty?

        feel better my friend,
        Evan Jerkunica

  101. Lulu says:

    I always have had good bowel movement until I took antibiotics for my ear infection. It sort of has upset my stomach so I ended up with heart burn, gas and acid reflux. I started on a 20 billion probiotics and it was great. The heartburn disappeared, and I was barely gasing. But I realiZed I haven’t been to the toilet for 3 days now. I do have a little bowel movement but it is very little. Should I worry? How long do I have to wait for the side effects to kick off?

    • evan says:

      Hi Lulu,

      The side effects really depend on the person. I would start by cutting down the dosage. Could you take them every other day? Take fewer each day?

      to your health,
      Evan Jerkunica

  102. Allison says:

    Question: I am concerned about beginning probiotics as the bathroom at work is QUITE a walk. The ones I purchased are in capsule form, can I open them and start with say 1/2 a capsule and move up from there? Thanks, very helpful information here btw..

  103. Kez says:

    Ive been plagued with thrush for years now including scalp an hairloss problems ive also had very loose bowels in the morning so i thought id try taking probiotics.Been taking them for two weeks now scalp feels alot better an believe it or now hairloss has decreased tremendously!been taking 2×3 billion however been very bloated an bowels have really slowed down!i will cut it down to one capsule a day then go back up to two daily!probiotics are amazing an i wished i started taking them years ago might have kept my beautiful curls!!!

    • evan says:

      Hey Kez,

      I’m glad some of your symptoms are improving…do your best to work through the side effects. I like that you’re cutting down the dosage, that should help reduce the side effects.

      to your health,
      Evan Jerkunica

  104. John says:

    Starting taking probiotics, and noticed after day 3, after I eat I have a feeling of dizziness which then causing some anxiety because this isnt normal for me to happen. I see a previous comment about it not being a normal side effect. Has anyone else been experiencing this sort of a thing?

    Been taking – 1 Pill a day of a 1B culture pack,

  105. Lilly says:

    I took a probiotic as the recommended doseage stated. At first I felt good, day 3 I got so sick! I had awful gas, bloating, belching, pain in my ribs, stomach, and center of my back and right side. constipated, I was miserable. I missed 2 days of work, laid up in bed for a week. I could not eat, so nauseated. After 14 days, I stopped taking the Probiotic. The symptoms stopped in 24 hours. Thank God. I have Permicious Anemia PA. I will never take Probiotics ever again. If you have Anemia, seek your Physicians approval before taking Probiotics. Its not safe if you have a pre-existing condition.

    • evan says:

      Thanks for sharing your experience – these side effects can be complicated…it could is more complicated than just having Permicious Anemia.

  106. Jourdan says:

    Hi! I’m new to probiotics. Can they cause anxiety? I tried coconut oil and it gave me severe panic attacks because of the “die off” and I don’t want the same thing to happen with this. I’ve heard that once you get use to probiotics they can take anxiety away but I don’t want to suffer from panic attacks again.

    • evan says:

      Hi Jourdan,

      I have not heard of probiotics causing anxiety…they have been shown to “improve mood and health outlook”.

      If you’re afraid of the die-off, then make sure to take a low dose of probiotics. Start with a brand that has 1 billion CFU, and take just 1 pill and wait 3 days to make sure everything is fine.

      Then if everything is fine, work up the frequency to 1 pill every day. Then if that’s fine, take 2 pills a day, etc. Good luck!

      to your health,
      Evan Jerkunica

  107. Steph says:

    Hi, I have recently followed a candida diet and protocol to treat candida-the latter part or the regime required probiotics which I’ve been taking 50 billion per day for 3 months now. During the last few weeks I have increased to 350 per day and felt really good. I showed signs of clearing such as nasal mucus. I continued to increase as I am trying to regulate my bowels. For my 42 year life I have generally only had bm every 4-9 days. During last year they are 2x daily – alternate days. I accidentally increased from 350 to 550 per day too quickly and had a fever, headache, glands ached, discharge, sore mouth. These have cleared over last week and I stopped all probiotics. My Q is how quickly can I safely increase probiotics again. Should I start right back from 50 billion or would I be safe to move fairly quickly to about 250 billion then slowly from there. Also I was diagnosed with rhuematoid arthritus 1 yr ago -which started my journey to health and candida recovery. I noted whilst on the probiotics and at the end of my candida plan that my RA had finally gone into remission. Then when I overdosed on probiotics some swelling of joints returned. I believe this to be because of toxin build up or is it something else? I read that although probiotics don’t colonise if you take them for 6-12 months you should then be able to lower the dose back down is this true? Lastly, I did have some constipation with the probiotics and so took pysillium husks at bedtime to help. Will this sweep the probiotics out if my gut though?

    • evan says:

      Hi Steph,

      Congrats on your progress on improving your health.

      To answer your question, if I were you I’d start back up as slowly as worked for you before. You don’t want a repeat of too big an increase.

      You would have to check with a doctor on where the Swelling symptoms come from, but in my non-medical opinion it likely comes from detoxing from the overdose of probiotics and moving all the toxins out of your body.

      Yes people often need to take probiotics for 6+ months for long lasting effects…many of the probiotic research studies have patients taking probiotics for 6 months to 24 months for long term beneficial. Other people will need to just take a few months of probiotics to get full beneficial effect. Given your challenges with Candida, I would bet you’ll need a longer course.

      I don’t know if pysillium husks will sweet out the probiotics. I don’t have access to research that suggests it would…and I would assume that any strong colonies of probiotics you have would not be hurt by the pysillium husks.

      I do know from my own experience that you need to take TONS of water with pysillium husks…if you want proof, just but a dose of pysillium husks into water and see how large they grow because of all the water the absorb :)

      And again, congrats you on taking control of your health!

      to your health,
      Evan Jerkunica

  108. Melanie says:

    Hi. I took 250mls of a kefir drink 2 weeks ago and have had diarrhoea ever since. Like every time I wee I poo loads!!!!!
    It seem to be slowing down in the last 2/3 days. Thank god, but I bought some probiotic capsules called Optibac, amazing reviews. Took my first dose yesterday morning with my porridge. This morning I was on the toilet for ages and I know I will be going again!!!!!
    Honestly, until reading your article I was more scared, thinking I had something seriously wrong. Still a bit worried, but I want to take them as I know they have so many health benefits. Will all this go away??!!!! Do you know of anyone that just can’t take them?! Thank you so much for listening to me witter on about myself.
    Melanie x

    • evan says:

      Hi Melanie,

      I have a good friend who if he takes about 3 Billion CFU, he will have diarrhea for 3 days straight.

      Personally, I can take about 10x the heaviest dose (which works out to 10×100 Bilion CFU) and I won’t get any side effects.

      It really depend on the person. If I were you I’d make sure that I am getting enough water, rest and trying eating different foods (maybe more meat/less meat).

      to your health,
      Evan Jerkunica

  109. carmel says:

    Fascinating page, thank you to all who posted here and especially Evan who puts in so much time to this.
    Something nobody else seems to have mentioned… I get terrible side effects from most medicines, including natural ones. Hving taken a lot of antibiotics etc I got sick of the doctor as well of being ill and decided to go on probiotics.
    You need to eat the right foods for them to feed off of.
    Garlic, onion etc. I ate some garlic and was very ill for a long time, so instead have onions to help it. Foods are prebiotics. YOu can google listst of them.
    I tried Dr Ohirras and found it quite good.
    But somehow I hvae a cough and sometimes get heady.
    Assumed this is acid reflux though do not get the other symptoms of it. It comes and goes.
    Switched to bacillus coagulan and found it helped.
    Then wanted a higher dose one so switched to a different make which contains 600,000,000 ! wow. Sounds like a lot, so much more than the first ones. But in real terms it is not much.
    Have had sore throat, rash, nausea, palpitations, diarrhea, brain fog, congested ears etc. Some of which has gone.
    The doctor is monitoring me for underactive thyroid.
    Most of these symptoms are the same as underactive thyroid and the blood tests will prove it.
    Am not totally well but am a lot better than I was a few years ago when I just took antiboitics and steroids and was often feeling so awful I cried and cried.
    Would you please respond if you can tell me of any other side effects you have had from taking biotics and if any of you have taken them to help with a cough or got a cough through them. Thank you and hvae a nice day.

  110. Mary says:


    I am experiencing mild diarrhea after beginning to take 90 billion strain probiotic. It’s not uncontrollable, just slightly loose stools and regularity. I want my body to get used to this strain, since I do believe my stomach needs the good flora and extra assistance. Should I wait it out and see how long the diarrhea lasts? It has only been 3 days that I have began this probiotic. (Ultimate Flora)

    • evan says:

      Hi Mary,

      It really depends on your level of comfort. Personally, if I had side effects for longer than 5 days, I would cut the dosage in half or take a break for a few days.

      to your health,
      Evan Jerkunica

  111. kez says:

    Could itchy spots that look like bites be part of the detox? I stopped taking mine for a couple of days but only because i forgot an realised when i started them again the spots that looked like bites started to itch again! Strange there isnt many of them however they are very itchy indeed…but i will continue because the benefits are outwaying the side effects! I still think probiotics are brilliant!

  112. kez says:

    Oh an Evan my bloating an constipation has stopped now….took a while tho dig enzymes really really a senna at some nights also!

  113. Red says:

    Hello, I started off taking probiotics 10 billion for a month things seem to be going great i even noticed less cellulite on my inner thighs and felt lighter and i moved quicker had a little pep in my I had nice bowel movements too. I then decided togo higher since things was going great then i decided to try Renew 90 billion probiotics and after couple weeks of taking this one i seem to have lost m guess appetite could taste my foods. Is this normal? Well i stopped for a couple of weeks now and my appetite is back.

    • evan says:

      Hi Red,

      You did the right thing…if you experience too intense of side effects it’s best to just stop the probiotics :) And as you saw, everything went back to normal after a bit.

      Your side effects aren’t typical, but they do sometimes happen…though losing your sense of taste is very atypical.

      to your health,
      Evan Jerkunica

  114. Joan says:

    Hey evan. Thank you for taking the time to answer the many comments. Much appreciated. I took my first probiotic last evening with a light meal. This morning after breakfast, I had a normal bowel movement, but that was followed by three quick bouts of diarrhea. I drank a glass of h20 in between each trip to the bathroom. Seems like it’s stopped for now, but I feel a little nauseous. Is it typical for the probiotic to work that quickly? Just took me off guard. No doubt I have unhealthy bacteria that needs to be cleansed.

    • evan says:

      Hi Joan,

      Thanks for your question!

      Yes – probiotics can work very quickly (and violently). Typically people see changes within a week – though many people see no changes for 3-4 weeks.

      take care,
      Evan Jerkunica

  115. Chris says:

    I was in a really bad car accident and the doc had me on a lot of pain meds. About a week ago I quit the meds and started taking probiotics. I’ve had a lot of the systems listed including diarrhea, nausea, and abdominal pain. How exactly do the meds affect the stomach and what are the probiotics doing?

    • evan says:

      Hi Chris,

      I don’t know exactly how pain medications and your digestive system interact. I’d chat with your doctor about the specifics of how that works. But I do know that as a general rule of thumb in holistic health communities, large doses of anesthesia should be followed up with probiotic supplementation.

      The good news is that there’s TONS of research proving that probiotics help with diarrhea…that is probably the single most proven condition to be helped by probiotics.

      I wish you a speedy recovery,
      Evan Jerkunica

  116. Delaney says:

    Evan, thanks so much for your time, advice and sharing your wealth of information.

  117. Mallory says:

    Good Morning,

    My daughter is 2.5 and has suffered from eczema since 3 months of age. It was recommended to try a probiotic to help improve her gut health because along with eczema she has bowel issues. She recently has had quite a few horrible flare ups from weather change and a gave exhausted All topicals so
    I am not trying to repair from the inside. She is also allergic to egg, tree nuts, and peanuts. We started giving her 1/8 tsp of Maxi Baby Powder Probiotic and she had a horrible outbreak about 15 minutes after! Is this normal? I am nervous to continue the use because of the immediate affect! Please help I just want to find a solution to this horrible skin issue!!

    • evan says:

      Hi Mallory,

      My name is Evan and I’m the founder of this site…I am NOT a doctor in any way, shape or form…and I don’t claim to be.

      I would talk with your doctor about this issue with the probiotic side effects…I don’t think a bad breakout after 15 mins is okay. Maybe your doctor would recommend a much smaller dose than the 1/8th of a tsp.

      Some people need to start with 1/10th the recommended dose…and build up from there…please chat with your doctor.

      Another probiotic folk remedy is to have very small amounts of this probiotic drink called water kefir. It’s a sour, drinkable yogurt often used in Russia. Ideally it should be made with the best milk you can find (from grass fed cows, raw, organic if possible). Once again, check with your doctor on if this is right for your daughter.

      to your daughter’s health,
      Evan Jerkunica

  118. Joan says:

    i have been taking a number of supplements and a multivitamin each day for years. Recently, I have started taking Mega Flora Probiotics, but wanted to ask if it’s alright to continue to take vitamins/supplements. Do they interfere with the absorption of the Probiotics or work against it?
    Thank you.

  119. Robin says:

    My daughter (25) has terrible acne. Literally we have tried everything. Our newest approach was to treat this from the inside. She is eating more vegetables, no processed foods, lots of water and is now taking pro biotic and turmeric. We are about 2 weeks into this and she has started to get more acne. I noticed you mentioned that that acne could be part of the detox process-can you respond to this? I think it must be a good thing that more garbage is coming to the surface and leaving her body. Thoughts?

    • evan says:

      Hi Robin,

      We do some amount of waste removal through our skin – how much really depends on the person in my observation.

      For example, I am very prone to dandruff…and if I’m not taking care of myself, flakes will follow (sometimes really large flakes if I’m way off)…my body order may also become more smelly…and occasionally I will get a few pimples on my face/body as well

      It could be your daughter is detoxing…it would make sense given all the new substances your daughter is putting into her body.

      It could be that your daughter isn’t able to digest raw salad well or new veggies that she’s eating, and she’s worse off by eating “healthy”…and this is why her acne is worse…or it could be the tumeric or probiotics.

      So you may need to look beyond just “acne” to see if your daughter is improving or now. The list below gives me a more complete picture of what’s happening in my body:

      Things that tell me I’m doing things right:
      -I have strong energy
      -I can concentrate well
      -I am in a neutral to good mood
      -I don’t have anxiety
      -I am not extra hungry
      -I feel satisfied after eating
      -I can last 4 hours between meals (with or without a small snack)
      -My stools are easy to pass and well formed
      -I poop around 12 inches of matter a day
      -I don’t smell bad
      -My breath doesn’t kill people right when I wake up
      -I am not bloated
      -I don’t have acne
      -My sex drive is strong
      -My dandruff is extremely minimal or non-existant
      -I can adjust well to being a bit cold or hot
      -I don’t feel like I’m on the verge of being sick.

      Who’s to say her menstrual cycle isn’t causing more acne? If she’s been feeling super low energy, or hasn’t felt full in these two weeks, then it could be that the food is wrong. Or she doesn’t do well with the probiotics she’s taking.

      For me, here’s what I need to do daily to feel healthy and have symptoms of health:
      -eating well for me (this takes time to figure out and changes day to day)
      -drinking lots of water
      -avoiding processed sugar
      -moving and exercising daily
      -going to sleep on time (before 10pm)
      -having a solid mental attitude
      -making sure to spend time having fun

      What do you think? You can email me if you’d like to speak further about this.

      to your (daughter’s) health,
      Evan Jerkunica

  120. Robin says:

    Thank you Evan for your response.
    I will keep you posted on our progress! I am hopeful that we will win this battle!


  121. Arianna says:

    I started taking probiotics 3weeks ago and didn’t have any side effects. However,3rd week in and I am starting to have gas and some diarrhoea. Is this delayed effect normal? Thanks!

    • evan says:

      Hi Arianna,

      Yes, it’s not uncommon for probiotics to have no side effects at first, and then start having some later. If I were in your situation, I would consider stopping the probiotics for a week and see if the diarrhea goes away.

      Then, you can start back at a lower frequency and slowly increase the frequency again.

  122. David says:

    Hi, I had an intestinal candida infection confirmed by stool test. I’ve managed to cure it with diflucan and strict diet. After that I started taking some extra high potency probiotics of 500 billion cfus per dose + I am taking once daily saccharomyces boulardii 5 billion cfu, the first week was okay but today I’m entering my second week and I have some extreme stomach pain almost like heavy burning sensation. is this some cleansing side effect?

    • evan says:

      Hi David,

      That is not a typical side effect…did a doctor recommend you start at 500 Billion CFU? In my personal experience it’s wise to start under a 100 Billion for sure, and many start under 10 Billion…do your own research and ask your doctor, but that sounds like a very large dose to me.

      Can you do 1/2 a pill or less to step it down?

  123. Victoria Hochman says:

    I starting taking 5 billion Natures Way and I completely exploded with bowel issues. It took me 3 days to realize it was the probiotic. I stopped taking it. I actually felt energized and in a great mood when taking it, besides that debilitating side effect. After one week off them, I went back on breaking open the capsule and pouring a small amount in water. Ive been having bad gas now. Please let me know how I should proceed? Im obviously have some difficulty but want to continue as my joint pain is all but gone and my mood is much better. Thanks for anything you can offer.

    • evan says:

      Hi Victoria,

      If the the benefits outweight the gas, then maybe consider riding out the gas for a few days?

      Or maybe take the probiotic once every few days? Or try taking every less of the probiotic? Or take the probiotic with food…or take it on an empty stomach first thing in the morning.

      Those are the things I would try if I were you.

      I’d check with your doctor because I’m not a medical doctor!

      to your health,
      Evan Jerkunica

  124. Victoria Hochman says:

    I forgot to ask something quite important…. Do these side effects go away after you have detoxed or does it continue forever if you’re on probiotics?. I don’t eat sugar or carbs and eat a pretty clean diet. Im going to drink more water to flush my system out, now that Im taking probiotics. I need to know, is there light at the end of the tunnel?, (no pun intended). Thank you so much for taking the time to answer and guide me through this journey.

  125. Victoria Hochman says:

    FYI I have been in the best mood. Is mood change a side effect? If so, Im going to be an addict.

  126. Evelyn says:

    I just started taking probio due to i am diabetic, and the next day I have rashes and itchiness on both arms…after reading this now I understand I will just take one a day to see if it will decrease my itchiness. …I am also taking tegreen, Cholestin and marine omega, also my hydrochloride for my BP and atorvastatin for my cholesterol. …thank you

  127. Kelly says:

    Do you know if oil of oregano can be taken with probiotics?

    • evan says:

      Hi Kelly,

      Since oil of oregano is antimicrobial, you should take it at least an hour apart from your probiotics pills.

      to your health,
      Evan Jerkunica

  128. Arthur says:

    I took a 500 billion count 34 strains probiotic and then increased it to 700 billion a day. This cause me sever problems. Pain and bloating in my gut along with sinus blurred vision and other problems. I stopped taking the probiotic about 3 day ago but the bloating and other problems have continued and seam to be worse. What if anything can i do about this


  129. Tamica says:

    I just started a 30 billion CFUs probiotic and immediately after taking it I began to feel jittery, stomach started to hurt. It sent me to the bathroom and my heart is starting to race
    It didny say anything about these side effects is this bad

    • evan says:

      Hi Tamica,

      Hmm – typically you can’t feel probiotics for at least 1 hour at the very earliest – they have to go through you digestive tract before things start to happen.

      That being said, I would consider taking a lower dose (say 1/2 a pill or less).

      take care,
      Evan Jerkunica

  130. FS says:

    After taking antibiotics I started taking probiotics, both for my mouth and my gut. However, I did notice one perculiar side effect: huge bowel movements…I mean much larger than what my food consumption justifies. I’m like OMG huge: could this be all the bad bacteria being passed thru?

    • evan says:

      Hi FS,

      I recently took antibiotics and it screwed me up for about 6 months…so I empathize!

      It’s hard to say specifically if the probiotics or antibiotics caused the issue.

      I would keep an eye on it – but probably not anything serious. Consult your doctor if it gets worse.

      take care,
      Evan Jerkunica

  131. Cheryl says:

    Would it be normal to have bleeding with the diaherra caused by taking probiotics? I do have an ulcer and am scheduled to see a GI doctor soon. Think I will stop the probiotics until then. Your thoughts?

    • evan says:

      Hi Cheryl,

      No, bleeding + diarrhea is not normal with probiotics.

      I think it’s good that you stopped taking them.

      Please work with your GI doc and see what he recommends.

      take care,
      Evan Jerkunica

  132. Farrah says:

    After being on Antibiotics for a sinus infection I took Garden of Life for women (85 billion). I took 3 per day as directed on the bottle. I had the worst bloating and gas and heartburn and it got much worst as I continued. I could hardly eat. I took it for 2 weeks and thank god I found this site. I had never suspected the probiotics were the cause. I have discontinued the probiotics for 4 days and my symptoms are slowly going away. I still am somewhat bloated but I can see the rapid progress. I am very active and have a very healthy diet. I had never experienced these symptoms before. Although each person is different, I am listing what is working for me in getting over probiotics side affects, in case it will benefit someone else:
    1- I follow an alkaline diet ( no tomatoe, onions, garlic,etc.) during this transition period even raw fruits and veggies bother me. I basically use Dr Judith Kauffman reflux book as a guideline.
    2- I have alkaline water
    3- I am a vegeterian, I don’t eat meat ( I am sure there are lowfat meats that will work for meat eaters), during this transition period, for the first time in my life beans give me horrible bloating, gas. So I eat eggs, egg whites, brown rice, boild spinach, avacados, brown rice, toast,nonfat plain greek yogurt ( I like wallaby organic). small amounts of farmhouse sauerkraut ( caraway seed), some boiled vegatables. bananas, No alcohol. no milk, or cheese or greasy or fatty food. I prepare veggie stews with cuman and fresh grated ginger. During this transition period my stomach has a hard time digesting nuts ( never had problems before).
    4- Manuka honey, fresh ginger and chamomile tea have helped a lot with gas and heartburn.
    5- I have very small meals several times through the day and don’t eat out.
    6- I have found walking really helps me.
    7- For bad heartburns ( I never got heartburns before) zantac has really helped me. Though I go easy on them and have them when I need them.
    8- I don’t eat anything 3 hours before bed
    It is quite disturbing that probiotics do not list the side affects. I had no idea they could mess up my system so badly. I had never had any problems with my gut before this experience.

    Thank you so much for this site and comments.

    • evan says:

      Hi Farrah,

      You’re very welcome. I’m glad you found the problem.

      Thanks for sharing your health tips.

      I personally need lots of meat! But ya, walking and more intense exercise are key for me too.

      take care,
      Evan Jerkunica

  133. DSDM says:

    Not sure this is an active thread but I thought I would give it a shot. I am a 50 year old male. I have been on antibiotics for 35 years due to acne and then chronic sinus issues. Not surprisingly I also developed GERD. For 16 straight years, I took some form of a PPI. Also, I had a diet fairly heavy in added sugars. No one ever told me about probiotics.

    In September of 15, my stomach completely gave out. I became extremely ill and could not keep anything in. I went to a gastro. After doing all the normal testing, she indicted that I suffered from SIBO. Yet, more antibiotics. However, she did recommend probiotics and a massive change in my diet AND to discontinue all PPI’s.

    The next several months were brutal. In April of 16, I stopped taking PPI’s and took Pepcid as needed. I experimented with store bought probiotics for a while. Finally, in Sept of 16, I ordered perfect probioitcs (30B CFU’s, 15 strains) and changed my diet which included a drastic reduction in sugars. I figure my diet previous to the change consumed about 50 to 60 grams of added sugar. Now it is probably 6 to 8 grams daily, sometimes even lower.

    The good news 3 months later is that the GERD is gone. I have taken 2 Pepcids in 3.5 months. I suffered from Adult Acne. That has greatly receeded as well. I had a cold last month that, for the first time in 25 years, did not turn into a sinus infection.

    The bad news is that I still have gas/bloating, loose stools that don’t evacuate properly and have to go several times a day. Again, it has been a few days more than 3 months. I don’t want to stop. How long should I give the probiotics? Is this normal for someone who spent decades destroying his stomach? I did have a CAT Scan and nothing structurally wrong was found. I want to stick with this. I have definitely seen some benefits.

    • evan says:

      Hi DSDM,

      I’m glad you are seeing some improvements between the diet change + probiotics. I personally am not a fan of PPI’s so I’m glad when people get off them.

      When someone has been on antibiotics for 35 years, it would not surprise me if it took a while to see full improvement any faster than a year or 2.

      It’s also possible that you have other issues going on – there are many causes of loose stools. I’ll list some common ones below that you can check out:

          get tested for parasite and candida infections
          check for food allergies – gluten, soy, dairy, etc.
          i never stay on the same probiotics for 3 months – spend at least 1 month on another brand
          are you still on antibiotics for SIBO? antibiotics can cause loose stools as well
          have you tried swedish bitters before a meal? or some diluted lemon juice before a meal?

      Please consider checking those out and see if you can get improvements from those avenues.

      Obviously check all of the above with your doctor to see if there are good reasons not to do them – good luck!

      to your health,
      Evan Jerkunica

  134. DSDM says:

    Thank you so much. I have been tested for parasites and Candida and came up negative. I do avoid dairy at all cost! I would say my diet is low in gluten. My gastro didn’t seem to think it was an issue.

    I am not on the antibiotics for SIBO. Actually, my last round was a year ago. That was my 3rd round. I would see an extremely minor improvement that would go away as all as I stopped taking the drugs. My theory was that I literally had no good bacteria left so the bad bacteria would just repopulate after the drugs. In 16, I was only on antibiotics (knock on wood) for 5 days (levaquin) for a minor sinus infection.

    I will look into food allergies. I am so limited with what I eat now that I am concerned about loosing too much weight.

    I definitely want to stick with this and appreciate your feedback that it could take a while. If someone told me that I would feel this level of discomfort for the next year but would feel much better afterwards, I would take that deal. After I am through with my course of probiotics, I will switch brands. Is there a link anyone can provide that has brands of high quality and reputation?

    Thanks again for the reply. I really appreciate it.

  135. DSDM says:

    Sorry! “Provide a link that has brands of high quality and reputation?

  136. Amber says:

    I’ve somewhat been taking this for a week or so but not really remembering it everyday. When I did take it I was taking it after dinner, three pills as the bottle said. No problems. But I took it about 3 days in a row like that and now… I am miserable every time I eat. It’s now noon Saturday but Thursday night was the last I took it, I was up the majority of the night sick. But I was better in the morning but every time I ate I started feeling bad again. I ate a bit earlier and now I’m back to being miserable :( My stomach is “rolling”, oddly my upper back is hurting rather than my lower back, and of course every so often I have to run to the restroom. Would you suguest just cutting the dose or maybe just not take it everyday? I just want to feel better

    • evan says:

      Personally, I would stop taking it. But of course listen to your doctor if case he/she instructed you to take it a certain way.

  137. curious says:

    44 year old taking probiotics once a day (for the first time) and fish oil 1400 mg twice a day. Broke out with significant acne worse than even as a teen going through puberty. I was concerned it was the fish oil supplements, but never had this problem before taking a lower dose. Could it be the probiotics? recommendations?

  138. Renee says:

    I have developed itchy red bumps on the back of my neck and they itch to high heaven ! I took me a bit to figure out this maybe from the probiotics it was the only new thing introduced within the last 2 weeks. I will be stopping them for now.

  139. Elena says:

    I just started taking probiotics 1 week ago to help clear up my acne. I take one in a powder form, mixed in water in the morning and 2 capsules in the evening, along with zinc and a woman’s supplement. The last couple of days my acne has started to clear up but I’ve been bloated, constipated and have put on 5 pounds. What would you suggest I do?

    • evan says:

      Hi Elena,

      1st, I would introduce 1 new supplement at a time. That way you can be sure which supplement is causing side effects.

      Next, you could consider taking a lower dosage of the probiotic to see if you get the acne benefits, but not the bloating/constipation.

      See how that goes and shoot me an email after that.

      Evan Jerkunica

  140. Carol says:

    I have the packets of powder. Can I use half a packet, close up, refrigerate then use next time? One packet is too much for my system right now.

  141. Crissy says:

    Can probiotics cause nausea, stomach pain, and the need to use the bathroom more often? I just started taking some yesterday (started out with 2 capsules, as was the recommended dosage) and later that day those issues started popping up…. could it be the probiotics?

    • evan says:

      Hi Crissy,

      They can – as well as other things. If it’s a very serious case, consider seeking medical attention. If it isn’t that bad, you could consider just not taking the supplement any more. It’s up to you.

      To your health,
      Evan Jerkunica

  142. Deb says:

    Started taking Silverfern probiotics….took for about a week and a half and have developed severe itchy rash over most of my body except my face. Stopped taking a week ago, but the rash has not gotten any better and is driving me crazy. Is this an allergic reaction or should I keep taking the probiotic? I know there is a herkheimer reaction that can happen before you actually get better. I am just not sure, but I need this to get better. Thank you!

    • evan says:

      Hi Deb,

      It’s ultimately you and your doctor’s call. If I had a severe reaction, then I would stop taking them. But check with your doctor.

      To your health,
      Evan Jerkunica

  143. Jamie says:

    I have been urinating a lot. Is this a side effect of the probiotics? I did start to urinate alot until i started to take them. But i do have diabetes in my family and i am black american.

    • evan says:

      Hi Jamie,

      It could be – I am not sure. I would check with a doctor in you can. Otherwise I would consider stopping the probiotics and seeing if that fixes the urination problem.

      To your health,
      Evan Jerkunica

  144. Iching says:

    Ya..i took one time only..rashes occur on surround my neck and feet…i am thinking of stop it because not only rashes but swollen on my neck …and also feel bloated.. omg i didnt expect the reaction come so fast..should i stop?

    • evan says:

      Hi Iching,

      I personally would. But if it seems serious enough, consider going to a doctor. Or if a doctor prescribed you to take them, you should speak with a doctor before discontinuing their use.

      Feel better,
      Evan Jerkunica

  145. Valerie Bennett says:

    Just started on. Syn365. Is it okay with blood pressure meds telmisartan and amlodipine.

  146. Darlene says:

    The oly side effect I noticed for both my husband and I is tingling in the throat as if sore throat. I completely stopped the symbiotic and it went away. Been off for about 2 weeks and throat cleared up after 3 days. It was helping in the bathroom and for weight gain. Any suggestions?

    • evan says:

      Hi Darlene,

      As long as your doctor didn’t tell you a specific dose, could you try a lower dose or take it only every other day?

      To your health,
      Evan Jerkunica

  147. Alli says:

    Hello, I would like to thank you for all of your information. It had helped me out on a school project. I thank you for getting this information, so other people who need it for educational and health-wise, knowledge.

  148. Lee says:

    As I wrote previously, I was having problems with taking the VSL3 recommended by my GI for IBS. Terrible gas in my abdomen and chest. I cut back from one per day to one every other day which he said was OK. Still having the same issues after taking it for two weeks. Talked to a pharmacist at The company that makes and distributes VSL3. She said those side effects should only last 7-10 days. My doctor isn’t providing much information about options or safety factors in continuing or stopping the medication—just that if I have symptoms that bother me to stop taking it and see if they go away. What a revelation! If taking the medication has caused the symptoms, I would sure hope that not taking it would make them go away. Any experience like this with VSL3? Quit after two weeks or keep going?

  149. Em says:

    Been feeling rather ill lately. Body aches, headaches, nausea, etc… I started taking double my usual dose of probiotics. A couple days later, although I was mostly feeling better, I got a persistent bout of diarrhea. It’s helpful to read this article and understand how that maybe have happened. I will go back to my usual dose and see how things go. Thank you.

Leave a Reply

Your email address will not be published. Required fields are marked *

Free Probiotics Guide

Learn to feel better with the newsletter (and get a free probiotics guide). Tools

Our Most Popular Articles

Free Probiotics Buying Guide

Want to buy the best probiotics for you and your health? Then you should click here to download the Probiotics Buying Guide.

Featured Product Reviews:

1MD Complete Probiotics Platinum Review

read GutConnect 365 review

read Synbiotic 365 review.