Dr. Rose, M.D. (researcher)
Evan Jerkunica (writer)
Saccharomyces boulardii, also known as Saccharomyces cerevisiae, is useful for relieving diarrhea related illnesses, and also fighting some infections like H pylori.
S. boulardii was first discovered on lychee and mangosteen fruit in 1923. The French researcher named Boulard saw that natives in Southeast Asia chewed on lychee and mangosteen fruits when infected with cholera. S boulardii helped control diarrhea and nausea associated with cholerastudy.
S. boulardii, like other probiotic organisms, produces proteins and chemicals that inhibit the growth of pathogens. This allows healthy bacteria and yeast to flourish in the gut. These proteins inhibit pathogenic bacterial adhesion to the intestinal wall.
S. boulardii is helpful in the prevention of antibiotic-associated colitisstudy [Warila]. This is a condition where antibiotics disrupt the healthy bacteria in the gut and allow the overgrowth of a pathogenic gut bacteria, C. difficile. S bourlardii supplementation appears to be effective in adults and children. Because of its safety and efficacy, the use of S. boulardii as prevention was recommended in a Cochrane Reviewstudy. Another study evaluating the available literature agreed.study
If a person does contract C. difficile infection, S. boulardii also helps reduce the symptoms and reduce relapses.
S. boulardii is also helpful in the treatment of HIV/AIDS related diarrhea. People with this disability complication of HIV not only improved but gained weight. Even though HIV/AIDS patients are immunocompromised by definition, there were no complications seen after giving S. boulardiistudy.[Villar-Garcia]
Helicobacter pylori is known to be the cause of stomach ulcers. Adding S. boulardii to the usual triple therapy for H. pylori significantly improved treatment outcomes, with better eradication ratesstudy.[Namkin] In addition, treatment of H. pylori often results in diarrhea, and giving S. boulardii helped reduce that diarrhea.
The evidence of efficacy of S. boulardii in viral gastroenteritis is not as strong, more research studies are needed.
Personally, I always take S boulardi with antibiotics to help prevent antibiotic associated diarrhea.study
I also carry a bottle of S boulardi when traveling in case I contract food poisoning. Since it is a yeast it survives heat better than other probiotics.
There have been reports of systemic infection with S. boulardii seen in severely immunocompromised patientsstudy.[Lherm] While this is rare, it is potentially lethal. On the other hand, immunocompromised HIV/AIDS patients tolerate it safely. Overall, it is considered safe in healthy individuals. If you are immunocompromised, please work closely with a doctor before taking the probiotic S boulardii.
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